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Receiving Relay Access Denied message when trying to send mail

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Hello,

I have a client who getting the following error when sending a message:

domainname-com.mail.protection.outlook.com[207.46.163.215] said: 550 5.7.0 Relay Access Denied (in reply to RCPT TO command)

I think this is a Microsoft/outlook.com issue.

Please advise.

Have a great day,

Don


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